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起止时间:2020-02-15到2020-06-21
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Chapter 1 Structure and Function of Proteins Unit test
1、 The chemical bond between the A and B chains of insulin is
A:peptide bond
B:disulfide bond
C:phosphoester bond
D:ionic bond
E:hydrophobic force
答案: disulfide bond
2、 The characteristic of secondary structure in myoglobin is to have more
A:α-helix
B:β-pleated sheet
C:β-turn
D:Ωloop
E:βαβ motif
答案: α-helix
3、 Autoclave disinfection is to make bacterial proteins
A:denaturation
B:precipitation
C:ionization
D:dissolved
E:degradation
答案: denaturation
4、 The protein whose structural change can cause sickle cell anemia is
A:lactate dehydrogenase
B:pyruvate kinase
C:insulin
D:myoglobin
E:hemoglobin
答案: hemoglobin
5、 The amino acid that can form disulfide bond in protein structure is
A:Trp
B:Met
C:Cys
D:Pro
E:Ser
答案: Cys
6、 Protein denaturation is due to
A:conformation destruction of protein
B:depolymerization of protein subunits
C:proteolysis
D:changes in the primary structure of protein
E:breaking of peptide bonds
答案: conformation destruction of protein
7、 Secondary structures of protein mainly include
A:α helix
B:β conformation
C:β turn
D:motif
E:random coil
答案: α helix;
β conformation;
β turn;
random coil
8、 Which of the following descriptions about tertiary structure of protein are correct
A:All polypeptide chains with tertiary structure have biological activities.
B:Most hydrophilic groups are located on the surface of tertiary structure.
C:The stability of tertiary structure is maintained by covalent bonds.
D:Tertiary structure is three-dimensional arrangement of all atoms in a polypeptide chain.
E:Formation of tertiary structure is the result of interaction between side chain groups of a polypeptide chain.
答案: Most hydrophilic groups are located on the surface of tertiary structure.;
Tertiary structure is three-dimensional arrangement of all atoms in a polypeptide chain.;
Formation of tertiary structure is the result of interaction between side chain groups of a polypeptide chain.
9、 Compared with myoglobin, hemoglobin is characterized by
A:Having quaternary structure
B:Containing heme
C:Having cooperative effects between subunits during combination with oxygen
D:The oxygen dissociation curve is S-shaped.
E:The main function is to transport oxygen.
答案: Having quaternary structure;
Having cooperative effects between subunits during combination with oxygen;
The oxygen dissociation curve is S-shaped.;
The main function is to transport oxygen.
10、 The UV absorption properties of protein are due to the presence of
A:tryptophan
B:glutamic acid
C:tyrosine
D:aspartic acid
E:histidine
答案: tryptophan;
tyrosine
11、 Which of the following amino acids contain hydroxyl group
A:serine
B:phenylalanine
C:tyrosine
D:threonine
E:methionine
答案: serine;
tyrosine;
threonine
12、 When the pH > pI of protein, the proteins have positive charge.
A:正确
B:错误
答案: 错误
13、 Glutathione acts as an antioxidant through its thiol group (-SH) in the molecule.
A:正确
B:错误
答案: 正确
14、 Only those peptides with larger molecular weight containing 10 or more amino acids have biological activities.
A:正确
B:错误
答案: 错误
15、 Each subunit in the quaternary structure of a protein can exert its function independently.
A:正确
B:错误
答案: 错误
Chapter 2 Enzymes Unit test
1、 Which of the following statements about active center of enzyme is not true?
A:Binding of enzyme with substrate is limited to the small area of enzyme structure which is closely related to enzyme activity.
B:The essential groups may locate either in or outside the active center.
C:Usually consists of several amino acid residues adjacent to each other in the primary structure
D:Zymogen activation is actually the process of forming complete active center.
E:Binding of substrates can induce conformational change of the active center of enzyme.
答案: Usually consists of several amino acid residues adjacent to each other in the primary structure
2、 When [S]=2Km, the velocity of an enzyme catalyzed reaction equals to
A:Vmax
B:2/3Vmax
C:3/2Vmax
D:2Vmax
E:1/2Vmax
答案: 2/3Vmax
3、 The effect of temperature on the rate of enzymatic reaction is
A:When the temperature rises, the reaction rate increases, which is exactly the same as that of ordinary catalysts.
B:Low temperature may denature the most enzymes.
C:The optimum temperature is the characteristic constant of enzyme and is not related to the reaction time.
D:The optimum temperature is not the characteristic constant of enzyme. The longer the reaction time, the lower the optimum temperature.
E:All enzymes have the same optimum temperature.
答案: The optimum temperature is not the characteristic constant of enzyme. The longer the reaction time, the lower the optimum temperature.
4、 The inhibitory effect of organophosphorus insecticide on cholinesterase belongs to
A:Reversible inhibition
B:Competitive inhibition
C:Noncompetitive inhibition
D:Uncompetitive inhibition
E:Irreversible inhibition
答案: Irreversible inhibition
5、 Which of the following is the reversible inhibitor?
A:organophosphorous compound
B:organic mercury compound
C:organoarsenic compound
D:cyanide
E:sulfonamides
答案: sulfonamides
6、 Competitive reversible inhibitors of enzyme can make
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