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Chapter1 Introduction to Metabolism quiz1
1、 Which one below is NOT a kind of high energy compound?
A:ATP
B:G-6-P
C:Glycerate-1,3-bisphosphate
D:Phosphocreatine
答案: G-6-P
2、 Enzymes are potent catalysts because they:
A:are consumed in the reactions they catalyze.
B:are very specific and can prevent the conversion of products back to substrates.
C:increase the equilibrium constants for the reactions they catalyze.
D:lower the activation energy for the reactions they catalyze.
答案: lower the activation energy for the reactions they catalyze.
3、 Which statement about allosteric control of enzymatic activity is FALSE?
A:Allosteric effectors give rise to sigmoidal V versus [S] kinetic plots.
B:An effector may either inhibit or activate an enzyme.
C:Binding of the effector changes the conformation of the enzyme molecule.
D:Heterotropic allosteric effectors compete with substrate for binding sites.
答案: Heterotropic allosteric effectors compete with substrate for binding sites.
4、 A small molecule that DECREASES the activity of an enzyme by binding to a site other than the catalytic site is termed a(n):
A:allosteric inhibitor.
B:alternative inhibitor.
C:competitive inhibitor.
D:stereospecific agent.
答案: allosteric inhibitor.
5、 Which amino acid is NOT one that may be targeted for phosphorylation to modulate the activity of an enzyme?
A:Tyr
B:Ser
C:Ala
D:Thr
答案: Ala
6、 Which type of enzyme is responsible for attaching phosphate groups to specific amino acids?
A:a protein phosphatase
B:a protein kinase
C:a protein glycosylase
D:an ATPase
答案: a protein kinase
Chapter2 Carbohydrate Metabolism quiz2
1、 Which reaction in glycolysis requires ATP as a substrate?
A:hexokinase
B:glyceraldehyde-3-phosphate dehydrogenase
C:pyruvate kinase
D:aldolase
答案: hexokinase
2、 Which reaction in glycolysis produces ATP as a product?
A:hexokinase
B:glyceraldehyde-3-phosphate dehydrogenase
C:pyruvate kinase
D:phosphofructokinase-1
答案: pyruvate kinase
3、 During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD+ if glycolysis is to continue. The most important reaction involved in the reoxidation of NADH is:
A:dihydroxyacetone phosphate → glycerol 3-phosphate.
B:pyruvate → lactate.
C: isocitrate → α-ketoglutarate.
D:oxaloacetate → malate.
答案: pyruvate → lactate.
4、 The anaerobic conversion of 1 mol of glucose to 2 mol of lactate by fermentation is accompanied by a net gain of:
A: 1 mol of ATP.
B:1 mol of NADH.
C: 2 mol of ATP.
D:2 mol of NADH.
答案: 2 mol of ATP.
5、 In comparison with the resting state, actively contracting human muscle tissue has a:
A: higher concentration of ATP.
B:higher rate of lactate formation.
C:lower consumption of glucose.
D:lower rate of consumption of oxygen
答案: higher rate of lactate formation.
6、 Which compound CANNOT serve as the starting material for the synthesis of glucose via gluconeogenesis?
A:acetate
B:glycerol
C:lactate
D:oxaloacetate
答案: acetate
7、 An enzyme used in both glycolysis and gluconeogenesis is:
A:3-phosphoglycerate kinase.
B:glucose 6-phosphatase.
C:hexokinase.
D:phosphofructokinase-1.
答案: 3-phosphoglycerate kinase.
8、 Which statement about gluconeogenesis is FALSE?
A:For starting materials, it can use carbon skeletons derived from certain amino acids.
B:It consists entirely of the reactions of glycolysis, operating in the reverse direction.
C:It employs the enzyme glucose 6-phosphatase.
D:It is one of the ways that mammals maintain normal blood glucose levels
答案: It consists entirely of the reactions of glycolysis, operating in the reverse direction.
9、 In humans, gluconeogenesis:
A:can result in the conversion of protein into blood glucose.
B:helps to reduce blood glucose after a carbohydrate-rich meal.
C:is essential in the conversion of fatty acids to glucose.
D:requires the enzyme hexokinase.
答案: can result in the conversion of protein into blood glucose.
10、 Which statement about the pentose phosphate pathway is CORRECT?
A:It generates 36 mol of ATP per mole of glucose consumed.
B:It is a reductive pathway; it consumes NADH.
C: It is present in plants, but not in animals.
D: It provides precursors for the synthesis of nucleotides.
答案: It provides precursors for the synthesis of nucleotides.
11、 The metabolic function of the pentose phosphate pathway is to:
A:act as a source of ADP biosynthesis.
B:generate NADPH and pentoses for the biosynthesis of fatty acids and nucleic acids.
C:participate in oxidation-reduction reactions during the formation of H2O.
D:provide intermediates for the citric acid cycle.
答案: generate NADPH and pentoses for the biosynthesis of fatty acids and nucleic acids.
12、 Which compound(s) is/are a high-energy intermediate(s) in glycolysis?
A:fructose 1,6-bisphosphate
B:NADH
C:1,3-bisphosphoglycerate and phosphoenol pyruvate
D:fructose 1,6-bisphosphate, 1,3-bisphosphoglycerate, and phosphoenol pyruvate
答案: 1,3-bisphosphoglycerate and phosphoenol pyruvate
13、 Malonate is a competitive inhibitor of succinate dehydrogenase. If malonate is added to a mitochondrial preparation that is oxidizing pyruvate as a substrate, which compound would you expect to decrease in concentration?
A:citrate
B:fumarate
C:isocitrate
D:pyruvate
答案: fumarate
14、 Which compound is NOT an intermediate of the citric acid cycle?
A:acetyl-CoA
B:citrate
C:oxaloacetate
D:succinyl-CoA
答案: acetyl-CoA
15、 In mammals, what process does NOT occur during the citric acid cycle?
A:formation of α-ketoglutarate
B:generation of NADH and FADH2
C:metabolism of acetyl-CoA to carbon dioxide
D:net synthesis of oxaloacetate from acetyl-CoA
答案: net synthesis of oxaloacetate from acetyl-CoA
16、 Conversion of 1 mol of acetyl-CoA to 2 mol of CO2 and CoA via the citric acid cycle results in the net production of:
A:1 mol of citrate.
B:1 mol of FADH2.
C:1 mol of NADH.
D:1 mol of oxaloacetate.
答案: 1 mol of FADH2.
17、 Which factor is NOT associated with the oxidation of substrates by the citric acid cycle?
A:CO2 production
B:FADH2
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